SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01957408b36564b9f7e81ffa7c2679c85c1fdbe72268af4212b0e9e3bb1e191d' 
  AND token = 'NxomI6auqexvC0bDngeco/PIuy9Jsd2LDd2un0YXupY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}