SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c879afbaf22dcd4225454c248ed4ad74a24298686758b91f2a208225ad41015' 
  AND token = 'aHSf+me4Z5xvDlP5KsR1+8SBfRxzs5+75Vo1jBJoAvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}