SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef40962a96fe50f44e952dc92e31fec436ef2fcd1c9cd4f75d59706e3c85f730' 
  AND token = 'afcjlSbkRIevXyTlh8udrnv/jAdtWE7vLZnzhn1O5fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}