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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd88839126608f8bacb3c3930588f4b537075a1863e9eda3cfef156b924406653' 
  AND token = 'j65frgdhasBT6/3V65bv07EEw3S1qKAMTf2VyJRuaQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}