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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '041fa5e53d7fe391b7ffd790d56738a76adf45b0b7636d95370abea52b008d96' 
  AND token = 'iQoJP/BEAxdAVyz0bEndNo1xiNtRux4yWMBEK2rB5d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}