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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8485dce69aec2cdcb0a57a6e9fccce4a9b9451c63904deaa7b4685091c39653' 
  AND token = 'ffmijEz/14l4pfJkuY7kRlefHfCOZUsRWi9+IuYg5qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}