SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fee999ef17b0e18f540f48684adebdb92519d06f8d4f3cd37ee03a91e31d554' 
  AND token = 'YzbHAFQCcR32mfBbRfw3xVspm/fEISmCZEvogHRO0ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}