SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68d3ee572e28c3fc8269cc5428b085cd75a9e75206cf5661a0beb7f23208dac2' 
  AND token = 'MLbHS6BVoDrtffYKvQY0VufFH4cVlc/bRtMG6MOeoqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}