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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5590deb07fb3a1032261584410af21e9308f10974df90c07851b491723690278' 
  AND token = 'hphtw+saPr1764MRR6dlUy+stIrNxNSv0a2jCfXw+n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}