SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3191db29dac38218adb18d4273c0cf3fe333dd58c3939aa15bb60369968fdd4' 
  AND token = '4c2oeNKGSFbZxUgMeiO/5KXhnt8ZAXMBAUrKcCVyVFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}