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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3afc84ba4fcdf780a12d21d488c0e6e5a3d007d31d267de0f029c3b911c3b61' 
  AND token = 'bUZfkP94bqv8M9Vf6SKCY0d6uVjBH50dB0pToPv+hJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}