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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de88e22e98a57ba91a373dd3b3274ec316a1804f8dc52f0e842df944902ebb20' 
  AND token = 'w2L25TcBQnaANOcKtoAyclUSspckLMe125L4Ap7HQnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}