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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57df76570c5ebbaf1fafd459644711a9a73ca4db007b9f6af84c8a7977d996f3' 
  AND token = 'K0Q9FTk5YOKim0l2FN/CfVQPycCSKMt6ekTZJJM+qD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}