SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47e14b4f4dbfd3aa33af916b96102adfcf3dbd69a5d83803840633d7bb171805' 
  AND token = '48pD2fNeRWfIRA0LgRK7D0z9RDL3kxgTYcfXKjpdOGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}