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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34f9213d27d190b6cc766537b5c1e0105aad958b7d9eabbde602491d5e44f345' 
  AND token = 'xxJzJxkzZjHyk+ZFqnIn8ME0OLaLWLW5uA/t54B8dB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}