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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b140aabf144249f367ce76e8e6c054c1bd51549359974f2673dd8b981579f01' 
  AND token = '5YcFG9GcTlil9RKzR1H5h7Fpvsys5hu0JEkzXtfmSaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}