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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3218c45058f11665fd65ab2af3d6fb36b1222e74f638e87455c99e0f53712a75' 
  AND token = '3HOk4ALJRUexajUJaNhiJRO8299hMNgMHcm7wj2Q8WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}