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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c1f57bcea9784bc112f64aa9bf3d67884e89e98c28b29a85698811713e045a' 
  AND token = 'e0woQYYKTW28wj4W9hlzFw23O3S4UZiLP0z3kQxoCVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}