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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe895b4ea5b33c5da3a8a99a6cbfff298b5bcda3b649462a648c8a173a4d584' 
  AND token = 't+eFETwiOyDC0f4WJbbPkbbVkDoG8ATTNtP/vhtN2os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}