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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a3bf721f256bda0fa7a736f03efd45d311da5cad09f83e192b348c11cab3a3' 
  AND token = '7Kcv2nCsFJSJQd1sG5s0I9AyMqofxA1EllnWMRbmATU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}