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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad5ba195cf948605901ce93187ccb328dfa932b904cec8fc9c7c422b90dee59c' 
  AND token = 'N6E3V2CBDklozZrvSe+mUdsLmJCY3D8U5k6avOa8DV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}