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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472f716ab11d24a0d2f98bbe8b2272fd2f9f51784d6d589f8cece1ef37ae6e36' 
  AND token = 'LdM4TMIVujal3gwxOWqWf6AobS5/6L3FcNJcYl7eyyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}