SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c87b00ae7c14ef46e6f1bb251b2302424eab2b406c163f3176e1df895bb174b' 
  AND token = 'QSULud/N1Ng62ADidm1LBRicIEc+MEBRCZ7/alnrrdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}