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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d900fe4a5861dd1e35522f5dcbd645658d80bcf76db65cebf810e8a1257586c' 
  AND token = 'GypBf9N6DTHRyEhlvmnlw6hc+iXsrezcu61FTniLUv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}