SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e8b4dd5a60954635e1d455ed9d844ca700d7d0b1ed03566d1a31a7525b625d' 
  AND token = 'pSkA+e6MAT9nn4O5NBaR1FTD4YQiFvS+1WTsyBorxXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}