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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dafaa2ee342bab44995b71a7eb14f77da0fe4b9137d1ffba3241b305dadc9d1' 
  AND token = '8cEO0YVbn5UTXYG6H9wxkMzsBfhHj4PTjniSssBfmD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}