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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ac6e50071bb074f5c44b442fa90c2ea2b1290560acd99a6da42d83be7e07bc' 
  AND token = 'mmmlPpzxcQMTU4OsythkPtegyfGg31r3LHZhRJgcNEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}