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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180d80822821baa9987dd42344702aae491357c45407bd5a759e6d3378e723e9' 
  AND token = 'o2+gvDpFGrSRtTEobSsBpXFh8KahSBh4eIsObCRkrz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}