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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad34db0a6a7092aa10e2e2c5d2e8aa4c5a7268529c5e34d75f74474b752f066' 
  AND token = 'zaHHRZ1mVzPn17GhwzHki/lWqaDj6x1JLFANysuttPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}