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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5dc69cb7448b3f29e81a8a747f1d111ee6949712b9f466edb9f022d7035a75' 
  AND token = 'u+EAIhDi8KFS8bLnVSY19rD/HfSkEq7FdiBUwvkZero=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}