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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ded4617c1e6c32d5413f3553bfc6e99614116d53ae8ffd5cbed135f17b5a29' 
  AND token = 'IZ7CnNvq9IAghetINreXbY062AVNt0jmPuM1E3nlqHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}