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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c84a98f6583868b42d27e680e3c20b7fe2c8407a146ca21cb11b428950b622d1' 
  AND token = '+c2wtHEe7QTalt8L/PPJhK0mt8UHwJGe+WKNmRPPifI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}