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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e491a181a3692f9239c0a60a7aa4801ffe1c009f3f22a9b31ce4a4ab601d3e' 
  AND token = '+0+RfBz0lza+FmycfWFpaOhlb0URSmD52GkqCD8fSRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}