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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e8b486a6c84df01a25ce1b602c94be2497801b9349b6bc8c2b47807dcd7fbd' 
  AND token = '4M+Xu2z6uFwUZMZFaqB4DP8IHjY9IWSd/MjCEOiKuHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}