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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e4e4a695af44037b9c63a110d167460ec282329c18fae74d615a4f9057e399' 
  AND token = '+3pWwreqA2y/H4sy5HbgvyeAEdrlYA+xBRBEQodqhSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}