SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e220057627f1604c0a7d7fcde88bce3194822fd73873f57fec7eec4d8c48d515' 
  AND token = 'EIbOxTIm8Sss77z5T57CnRz42hWZ6KoCjIYbHhd2Nwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}