SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f0345880c961362258b92d66be7c4ee834b4c95113822d69a482d819543f78' 
  AND token = 'iwIt63N4Aed3A2NvkDwkitYDpEwaqFtSCx662paohL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}