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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0df9e47ce123bc52ea6921feea2858c40b2907125436d28e22b6bb2deab3b54' 
  AND token = 'TV9UYNI5NeqbxeGsOgCtyZYacSa1aIWFeWs7irdtQ0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}