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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a63950c019be884067b81eba5fc06b57a1cd12fbbe513c673dc25b9a9fa341e' 
  AND token = 'EQ6SsBYuHYdIOKMVuTwOV6pW7lnKcvQ39LsoqA6c4nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}