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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186bf19d79cb5c091b09ce679512d8356f0f88a42c1361e7b648b808127fb96a' 
  AND token = 'A7UuQ6SC5Q+dkk2DcM6SuZyBjNagbRWD8b0gPh5w2AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}