SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f01a4ca27234a4569a6a9eb14cb5f3eb7b72194b5d60cb970b51682e7cd63ee0' 
  AND token = '+s4soaaJj0GXi+lBLpfV4p2NqCFZzhrn9fkrzOXL2Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}