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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e9262600c3fa4e5f5351f6d423dc5b224c4fc37b701a55da3c807887f57168' 
  AND token = '3DEfKMXdjx+zv3f0ObPJUJcDA48HJQLQXBUOWEY3xgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}