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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f75f801308397f65a24b226eff83cbb409e50e2461aefbfc6cebd9a46f0fd5' 
  AND token = 'FFmlCENyf1cBahy3nKjf8IP2XW0VwxRd/mGRJ8kxy9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}