SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73bd2e00d91bf4dcc849091eb7f784ce65cfe3c084333a6676f032d06637c5c8' 
  AND token = 'PCEE6rAMs0ok9xfwavt2HLLLdoeX8ZAodUmSVoTuvGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}