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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b2100216eefb754818031aae0e486a135875c225b0151dbb50cbc65dc17c8f' 
  AND token = 'mPk+VXcqKyO5fMJOUM7R9HJngc+QP1bgDxztcnVksWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}