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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2285e8b173f5155f7f1175fb999ced7fb32dcf9a78ff2d2ff531979b1a75d40' 
  AND token = 'YAjliZ80H7eipoiqQgKvbpYTIp29hKXeYG1fZz0A08M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}