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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1800723162af3dcce0588cceb89ff199c1a12a8f840da6be748a96d16a595afa' 
  AND token = 'dSE9RA2r+Hj1m71XbLLp7FyTrlYh6b/3UY4QScJSJ1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}