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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd337380450a3c631a79d3ebd68c2275479611528d650f9c770e1ab52cc77ed8' 
  AND token = 'dd2tIXvWme45QqS296in/Pew03k36bI+uWNYOD3aRns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}