SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7471ba18ddbe6c53a1d87049e23db4c3c48913ae024127746b9e5d1f6e25bc20' 
  AND token = 'SM8d0G2ODE1ZSQ5yZzR0KM3fjI394rI5z0luD4F2t/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}