SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2948ddffaaec78d7856228c2c6f7f433063f9a730aac8c0c013ad81bb9930d07' 
  AND token = 'yfLCcR0iSN3o8+/tQ6IHq36c61UHPwVeuMRWfxWkWt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}